Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5781
Gene Symbol: PTPN11
PTPN11
Q06124 protein tyrosine phosphatase non-receptor type 11 702 0.385 0.923 1.00 1.000 definitive 0.987 301 58 2001 2020
Entrez Id: 2688
Gene Symbol: GH1
GH1
P01241 growth hormone 1 Signaling 686 0.373 0.923 3.0E-02 0.100 None 0.947 19 1 2004 2020
Entrez Id: 8216
Gene Symbol: LZTR1
LZTR1
Q8N653 leucine zipper like transcription regulator 1 152 0.547 0.808 1.0E-92 0.900 strong 1.000 14 1 2014 2020
Entrez Id: 4609
Gene Symbol: MYC
MYC
P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 821 0.344 0.923 1.00 0.010 None 1.000 1 0 2020 2020
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase Enzyme modulator 1213 0.320 0.923 7.9E-04 1.000 definitive 0.985 68 17 1993 2019
Entrez Id: 6654
Gene Symbol: SOS1
SOS1
Q07889 SOS Ras/Rac guanine nucleotide exchange factor 1 Enzyme modulator 261 0.485 0.808 1.00 1.000 definitive 0.969 64 23 1991 2019
Entrez Id: 5894
Gene Symbol: RAF1
RAF1
P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 470 0.418 0.885 0.85 1.000 definitive 1.000 59 19 1992 2019
Entrez Id: 673
Gene Symbol: BRAF
BRAF
P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1228 0.319 0.846 1.00 0.770 moderate 1.000 34 18 2003 2019
Entrez Id: 8036
Gene Symbol: SHOC2
SHOC2
Q9UQ13 SHOC2 leucine rich repeat scaffold protein 97 0.593 0.769 1.00 0.800 disputed 0.957 23 1 2009 2019
Entrez Id: 6016
Gene Symbol: RIT1
RIT1
Q92963 Ras like without CAAX 1 Enzyme modulator 184 0.527 0.808 0.13 0.900 definitive 1.000 22 13 2013 2019
Entrez Id: 4893
Gene Symbol: NRAS
NRAS
P01111 NRAS proto-oncogene, GTPase Enzyme modulator 611 0.390 0.808 0.49 0.780 definitive 1.000 21 4 2000 2019
Entrez Id: 5604
Gene Symbol: MAP2K1
MAP2K1
Q02750 mitogen-activated protein kinase kinase 1 Kinase 389 0.439 0.846 0.90 0.680 limited 1.000 14 3 2007 2019
Entrez Id: 5605
Gene Symbol: MAP2K2
MAP2K2
P36507 mitogen-activated protein kinase kinase 2 Kinase 177 0.534 0.731 0.97 0.640 limited 1.000 11 2 2007 2019
Entrez Id: 22808
Gene Symbol: MRAS
MRAS
O14807 muscle RAS oncogene homolog Enzyme modulator 113 0.590 0.731 0.92 0.560 limited 1.000 8 1 2013 2019
Entrez Id: 5500
Gene Symbol: PPP1CB
PPP1CB
P62140 protein phosphatase 1 catalytic subunit beta Enzyme 105 0.601 0.577 1.00 0.350 1.000 5 0 2016 2019
Entrez Id: 22800
Gene Symbol: RRAS2
RRAS2
P62070 RAS related 2 Enzyme modulator 48 0.656 0.500 0.97 0.620 strong 1.000 3 0 2014 2019
Entrez Id: 5598
Gene Symbol: MAPK7
MAPK7
Q13164 mitogen-activated protein kinase 7 Kinase 127 0.553 0.654 3.1E-03 0.010 None 1.000 1 0 2019 2019
Entrez Id: 58499
Gene Symbol: ZNF462
ZNF462
Q96JM2 zinc finger protein 462 Transcription factor 34 0.711 0.462 1.00 0.010 None 1.000 1 0 2019 2019
Entrez Id: 92170
Gene Symbol: MTG1
MTG1
Q9BT17 mitochondrial ribosome associated GTPase 1 59 0.621 0.769 1.3E-02 0.010 None 1.000 1 0 2019 2019
Entrez Id: 369
Gene Symbol: ARAF
ARAF
P10398 A-Raf proto-oncogene, serine/threonine kinase Kinase 56 0.619 0.654 0.96 0.010 None 1.000 1 0 2019 2019
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
P01112 HRas proto-oncogene, GTPase Enzyme modulator 698 0.378 0.885 8.0E-02 0.640 1.000 8 4 2006 2018
Entrez Id: 22882
Gene Symbol: ZHX2
ZHX2
Q9Y6X8 zinc fingers and homeoboxes 2 Transcription factor 172 0.510 0.654 3.4E-02 0.050 None 1.000 5 1 2011 2018
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
P05019 insulin like growth factor 1 1206 0.318 0.885 0.27 0.030 None 1.000 3 1 2009 2018
Entrez Id: 998
Gene Symbol: CDC42
CDC42
P60953 cell division cycle 42 Enzyme modulator 327 0.458 0.846 0.79 0.020 None 1.000 2 0 2018 2018
Entrez Id: 406971
Gene Symbol: MIR195
MIR195
microRNA 195 180 0.496 0.769 0.010 None 1.000 1 0 2018 2018